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Chloral Hydrate faces supply disruption

The Department of Health and Social Care (DH) has issued a Medicine Supply Notification (MSN) for Chloral Hydrate 143.3mg in 5ml oral solution.

Chloral Hydrate 143.3mg in 5ml oral solution will remain out of stock until September.


Specials manufacturers have confirmed they can manufacture chloral hydrate 143.3mg in 5ml oral solution to meet demand of the licensed product.

The specials manufacturers including Ascot labs, Alium Medical, and Target Healthcare have confirmed that they can manufacture chloral hydrate oral solution.

The above products are not batch manufactured and the supplier will only provide a certificate of conformity (CoC).

Suppliers providing batch manufactured products will provide a certificate of analysis (CofA).

If there is currently no listing on dm+d for the imported product for prescribers to select using their prescribing systems an EPS prescription for unlicensed Chloral Hydrate 143.3mg in 5ml oral solution cannot be issued.

If a prescriber wishes to prescribe an unlicensed import, an FP10 paper prescription should be issued as ‘Chloral Hydrate 143.3mg in 5ml oral solution (Special Order)‘ and endorsed by the pharmacy as a non-Part VIIIB special.

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